COVID-19 has highlighted historic health disparities among people of color (POC) due to social inequities. POC have an increased risk for severe illness if they contract COVID-19, as this population has a higher number of underlying health conditions. There are also high levels of anxiety, depression, stress-related disorders, substance use and suicidal ideation than non-Hispanics. Today more than ever, it is crucial to provide cultural and linguistic prevention programs and Evidence-Based practices that are effective for substance misuse, suicide prevention and mental health programs for POC. Prevention Specialist providers have been positioned to help address these risk factors, but must now navigate their roles in the current pandemic context. This interactive virtual session will outline the unique challenges, opportunities, best practices and strategies for moving forward.